Reactions may vary from person to person. During use, some users may feel a slight tingling sensation in their nose or airways. At higher CO₂ levels, an increased respiratory drive may occur—the natural urge to breathe a little deeper or faster. This is a normal response of the respiratory center. After use, some users report feeling more relaxed, having a clearer head, or experiencing an increased sense of energy, while others do not notice any immediate change. The intensity of these reactions varies from person to person.